刘 佳，副教授，硕士生导师。

2017年获得南京大学博士学位，随后前往新加坡国立大学从事博士后研究工作，2021年作为高层次人才加入拼搏体育官方。研究方向为单细胞分析技术及其在生物医药中的应用研究，目前已经发表学术论文十余篇，主持参与国家重大仪器项目，国自然青年项目和江苏省青年项目3项。

获奖：

2017年，中国分析测试协会科学技术奖一等奖，第二完成人（2/9）

承担项目：

1.   国家自然科学基金（青年项目），2021年，主持

2.   江苏省青年科学基金项目，2020年，主持

3.   国家重大科研仪器研制项目，2016年，主要完成人

代表性论文：

1.    Jia Liu, Hui He, Dan Xie, Yanrong Wen and Zhen Liu*, Probing low-copy-number proteins in single living cells using single-cell plasmonic immunosandwich assays. Nat. Protoc., 2021, 16, 3522-3546.

2.    Jia Liu, Danyang Yin, Shuangshou Wang, Hong-Yuan Chen, and Zhen Liu*. Probing low-copy-number proteins in a single living cell. Angew. Chem. Int. Ed., 2016, 55, 13215-13218.

3.    Jia Liu, Yanrong Wen, Hui He, Hong-Yuan Chen and Zhen Liu*. Probing cytoplasmic and nuclear microRNAs in single living cells via plasmonic affinity sandwich assay. Chem. Sci., 2018, 9, 7241-7246.

4.    Jia Liu, Guoyun Sun, Shih-Chung Wei, Song Guo, Weikang Nicholas Lin and Chia-Hung Chen*. Nanoplasmon-enhanced drop-screen for high throughput single-cell nucleocytoplasmic miRNA profiling. Lab Chip, 2020, 20, 1939-1946.

5.    Jia Liu, Dan Xie, and Zhen Liu*. Probing nucleus-enriched proteins in single living cells via subcellular-resolved plasmonic immunosandwich assay. Analyst, 2021, 146, 2878-2885.

6.    刘佳，刘震*，单细胞分析技术研究进展，色谱，2016，34（12），1154-1160.

7.    Yanrong Wen, Jia Liu, Hui He, Shawn S. C. Li, Zhen Liu. Single cell analysis of signaling proteins provides insights into pro-apoptotic properties of anti-cancer drugs. Anal. Chem., 2020, 92, 12498-12508.

8.    Pir Muhammad, Jia Liu, Rongrong Xing, Yanrong Wen, Yijia Wang, Zhen Liu*. Fast probing of glucose and fructose in plant tissue via plasmonic affinity sandwich assay with molecularly-imprinted extraction microprobes. Anal. Chim. Acta., 2017, 995, 34-42.

9.    Qi Zhang, Jia Liu, Yueru Dong, Wei Li, Rongrong Xing, Yanyan Ma, and Zhen Liu, Gold nanoparticle-decorated Ag@SiO₂ nanocomposite-based plasmonic affinity sandwich assay of circulating microRNAs in human serum. ACS Appl. Nano Mater., 2019, 2, 3960-3970.

10. Yanyan Ma, Xinling Li, Jia Liu, Wei Li, and Zhen Liu. Convenient construction of orthogonal dual aptamer-based plasmonic immunosandwich assay for probing protein disease markers in complex samples and living animals. ACS Sensors, 2020, DOI: 10.1021/acssensors.0c00359.

11. Xueying Tu, Pir Muhammad, Jia Liu, Yanyan Ma, Shuangshou Wang, Danyang Yin, Zhen Liu*. Molecularly-imprinted polymer-based plasmonic immunosandwich assay for fast and ultrasensitive determination of trace glycoproteins in complex samples. Anal. Chem., 2016, 88, 12363-12370.

12. Pir Muhammad, Xueying Tu, Jia Liu, Yijia Wang, and Zhen Liu*. Molecularly imprinted plasmonic substrates for specific and ultrasensitive immunoassay of trace glycoproteins in biological samples. ACS Appl. Mater. Interfaces, 2017, 9, 12082-12091.

13. Lingli Zhou, Yijia Wang, Rongrong Xing, Jin Chen, Jia Liu, Wei Li, Zhen Liu. Orthogonal dual molecularly imprinted polymer-based plasmonic immunosandwich assay: A double characteristic recognition strategy for specifi detection of glycoproteins. Biosens. Bioelectron., 2019, 145, 111729.

14. Danyang Yin, Shuangshou Wang, Yunjie He, Jia Liu, Min Zhou, Jian Ouyang, Baorui Liu, Hong-Yuan Chen and Zhen Liu*. Surface-enhanced Raman scattering imaging of cancer cells and tissue via sialic acid-imprinted nanotags. Chem. Commun., 2015, 100, 17696-17699.

 专利：

中国发明专利（已授权）

专利名称：一种不同亲和配基功能化的金基萃取材料及其在表面等离激元光学亲和夹心分析中的应用

作者：刘震，刘佳，尹丹阳，涂雪莹，Pir Muhammad，第二完成人（2/5）

专利号：ZL201610737470.5，授权日期：2020年2月7日

E-mail: jialiu@njtech.edu.cn